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Title: Treatment For Circadian Performance Deficits By Upmodulation Of Central Glutamate Receptors
UC Case No: 1999-136-1-ott
Categories: Pharmaceuticals: Sleep Disorders
Background: Alertness and general physical and mental performance are impaired during normal sleep periods compared to those during normal waking periods. Unlike stimulants such as caffeine or methamphetamine, certain glutamatergic enhancer compounds have been shown to improve memory and performace in tests conducted during normal sleep periods for both rats and humans.
Technology: Researchers at the University of California, Irvine, have tested certain compounds on rats that were subjected to maze tests during their normal sleep periods. The application of the drug caused a significant increase in the speed with which the animals completed the test.
Application: These compounds have potential application in neurobiological research and in the biomedical field for helping individuals adjust their circadian rhythm.
Contact: Ronnie Hanecak, Ph.D., Associate Vice Chancellor (Interim)
Office of Technology Alliances
University of California, Irvine
380 University Tower
Irvine, CA 92697-7700

Phone: (949) 824-7186
FAX: (949) 824-2899
Email: rhanecak@uci.edu
Patent Status: Pending
UCI School: Information & Computer Science
Department: -- No Dept Listed --