Home | Contact Us | Forms | Events | News | Links

OTA Resources

Quick Links


Send Us Your Feedback

Available Technologies - Search Results

Title: Triple Transgenic Mouse Model of Alzheimer's Disease
UC Case No: 2002-099-2-ott
Categories: Pharmaceuticals: Central Nervous System Disorders
Biotechnology: Assays, Diagnostics, Drug Targets and Screening Tools, Model Systems, Research Tools
Technology: University of California, Irvine researchers have developed a novel transgenic mouse model that contains the three major genes that contribute to the hallmark pathological features of Alzheimer's disease. These mice are exceedingly valuable for therapeutic investigations and for basic research aimed at understanding the behavioral, physiological, molecular/cell biological, and pharmacological processes leading to dementia in an animal model. Even though these mice contain three transgenes, the mice essentially breed as readily as a "single" transgenic line, greatly facilitating the establishment and maintenance of an animal colony.
Contact: Ronnie Hanecak, Ph.D., Associate Vice Chancellor (Interim)
Office of Technology Alliances
University of California, Irvine
380 University Tower
Irvine, CA 92697-7700

Phone: (949) 824-7186
FAX: (949) 824-2899
Email: rhanecak@uci.edu
Patent Status: U.S. Patent No. 7,479,579
UCI School: School of Biological Sciences
Department: Neurobiology & Behavior