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Title: Depth Profiling of the Skin Structure In Vivo
UC Case No: 2002-364-2-ott
Categories: Medical Imaging/Radiation: Other Imaging
Technology: University researchers have developed a photoacoustic probe contained within a handpiece for use in contact with the skin. The laser pulses generate acoustic waves at the subsurface absorption sites. It is believed that no known use of photoacoustics has been used for this purpose in the past. Previous probes of skin structure include biopsy and histology, and optical and ultrasound measurements. The photoacoustic method provides a non-invasive method, unlike a biopsy. It also is not subject to optical scattering and degradation of the signal, as the signal is acoustic. This method provides higher resolution (possibly 15 mm) than ultrasound. Additionally, unlike ultrasound, it induces the subsurface skin structures to become active acoustic sources depending on their optical properties.
Application: This device may be used in a medical clinic for analyzing melanin content in healthy skin or determining the depth profile of pathological skin conditions such as port wine stains and skin burns.
Contact: Alvin K. Viray, Senior Licensing Officer
Office of Technology Alliances
University of California, Irvine
380 University Tower
Irvine, CA 92697-7700

Phone: (949) 824-3104
FAX: (949) 824-2899
Email: aviray@uci.edu
Patent Status: U.S. Patent No. 7,322,972
UCI School: Beckman Laser Institute
Department: -- No Dept Listed --